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Product Information:

NS 3861

NS3861 is an α3β2 full agonist and an α3β4 partial agonist.

Cat. No.: EX-A5503    Purity: >98%
Chemical
Chemical structure of NS 3861


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg700In-stock
500mg1050In-stock
1g1650In-stock


CAS No.216853-60-0
Purity>98%
FormulaC16H18BrNO4S
Mol Weight400.287
ColorWhite to off-white
Statesolid powder
SolubilitySoluble in DMSO 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4°C, sealed storage, away from moisture and light; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Gade AR, et al. Enhanced Sensitivity of α3β4 Nicotinic Receptors in Enteric Neurons after Long-Term Morphine: Implication for Opioid-Induced Constipation. J Pharmacol Exp Ther. 2016 Jun;357(3):520-8. doi: 10.1124/jpet.116.233304. Epub 2016 Apr 11. PubMed PMID: 27068812; PubMed Central PMCID: PMC4885510.

[2]. Harpsøe K, et al. Molecular determinants of subtype-selective efficacies of cytisine and the novel compound NS3861 at heteromeric nicotinic acetylcholine receptors. J Biol Chem. 2013 Jan 25;288(4):2559-70. doi: 10.1074/jbc.M112.436337. Epub 2012 Dec 10. PubMed PMID: 23229547; PubMed Central PMCID: PMC3554923.
CoACoA of NS 3861

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