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Product Information:

NRX-252262

NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation, with an EC50 of 3.8 nM.

Cat. No.: EX-A5657    Purity: >98%
Chemical
Chemical structure of NRX-252262


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg550In-stock
50mg850In-stock
100mg1150In-stock
200mg1650In-stock
500mg2450In-stock


CAS No.2438637-61-5
Purity>98%
FormulaC23H17Cl2F3N2O4S
Mol Weight545.358
Color White to off-white
Statesolid powder
SolubilitySoluble in DMSO 8.33 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Kyle R. Simonetta, et al. Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nature Communications. 2019 March.
CoACoA of NRX-252262

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