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Product Information:

Nrf2 activator-6

Nrf2 activator-6, a tetrahydroisoquinoline compound, is a Nrf2 activator. Nrf2 activator-6 has an IC50 of 5 nM for inhibiting the Kelch domain-Nrf2 interaction (WO2021214470A1; Example 4) .

Cat. No.: EX-A15112    Purity: >98%
Chemical
Chemical structure of Nrf2 activator-6


For research only, Do not use for Human!

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CAS No.2728780-74-1
Purity>98%
FormulaC31H37ClFN5O5
Mol Weight614.107
ColorWhite to off-white
StateSolid
Shelf Life>3 years if stored properly
StoragePowder -20℃, 3 years; In solvent -20℃, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Cathy Louise LUCAS, et al. Tetrahydroisoquinoline compounds as nrf2 activators. WO2021214470A1.

CoACoA of Nrf2 activator-6
Smiles:OC([C@@](C)(CCC1)[C@@H]1C(N2[C@H](CN3C(CC4(C3)CC4)=O)C5=C(C(F)=CC(Cl)=C5CC2)OCC6=C7N(CCCC7)N=N6)=O)=O

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