NR2E3 agonist 1

NR2E3 agonist 1 (Compound 11a) is a small molecule agonist of the photoreceptor-specific nuclear receptor (NR2E3) with an EC50 value of less than 200 nM. NR2E3 agonist 1 can be used in retinitis pigmentosa research.


Cat. No.: EX-A8551	Purity: >98%

	Chemical structure of NR2E3 agonist 1

For research only, Do not use for Human!

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CAS No.	911211-69-3
Purity	>98%
Formula	C24H19ClN4O2
Mol Weight	430.886
Color	White to off-white
State	solid powder
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Wolkenberg SE, et al. Identification of potent agonists of photoreceptor-specific nuclear receptor (NR2E3) and preparation of a radioligand. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5001-4.
CoA	CoA of NR2E3 agonist 1

Smiles:	O=C(C1CC1)NC2=CC=C(NC(C3=CC=C(NC(C4=CC=CC=C4Cl)=O)C=C3)=N5)C5=C2


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