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Product Information:

NPD4928

NPD4928, a GPX4 inhibitor, enhances RSL3 -dependent ferroptosis. NPD4928 binds to ferroptosis suppressor protein 1 (FSP1) and inhibits its enzymatic activity .

Cat. No.: EX-A10403    Purity: >98%
Chemical
Chemical structure of NPD4928


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg1245Inquire
1g2488Inquire


CAS No.956965-61-0
Purity>98%
FormulaC29H32N2O6
Mol Weight504.5742
ColorWhite to off-white
StateSolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4°C, sealed storage, away from moisture; In solvent -20°C, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Hiromasa Yoshioka, et al. Identification of a Small Molecule That Enhances Ferroptosis via Inhibition of Ferroptosis Suppressor Protein 1 (FSP1). ACS Chem Biol. 2022 Feb 18;17(2):483-491.

CoACoA of NPD4928
Smiles:O=C1OC2=C(C(C)=C1C)C(OCC(NCCC3=CNC4=C3C=C(OC)C=C4)=O)=CC5=C2CCC(C)(C)O5

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