NOX2-IN-2

NOX2-IN-2 (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with a Ki of 0.24 μM. NOX2-IN-2 inhibits ROS production derived from NOX2 in cells.


Cat. No.: EX-A12780	Purity: >98%

	Chemical structure of NOX2-IN-2

For research only, Do not use for Human!

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CAS No.	2648709-79-7
Purity	>98%
Formula	C25H25N7O3
Mol Weight	471.5111
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Jie Zang, et al.Targeting NOX2 with Bivalent Small-Molecule p47phox-p22phox Inhibitors. J Med Chem. 2023 Oct 19.
CoA	CoA of NOX2-IN-2

Smiles:	NC1=NC2=CC=C(C=C2C=C1)OCC3=CN(N=N3)CCOCCOC4=CC=C5N=C(C=CC5=C4)N


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