NOX-6-18

GPR132 antagonist 1 (GPR132-B-160, Compound 25) is a GPR132 antagonist with an EC50 value of 0.075 μM. GPR132 antagonist 1 has promote insulin secretion activity with an EC50 value of 0.7 μM.


Cat. No.: EX-A8304	Purity: >98%

	Chemical structure of NOX-6-18

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	685	In-stock
500mg	1085	In-stock
1g	1685	In-stock
2g	2485	In-stock
5g	4900	In-stock

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Synonyms	GPR132 antagonist 1
Synonyms 2	GPR132-B-160
CAS No.	898211-21-7
Purity	>98%
Formula	C18H17NO5S
Mol Weight	359.396
Color	White to off-white
State	solid powder
Solubility	DMSO : ? 100 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Wang, Jia-Le et al. “Functional screening and rational design of compounds targeting GPR132 to treat diabetes.” Nature metabolism vol. 5,10 (2023): 1726-1746. doi:10.1038/s42255-023-00899-4 [2]. CN116903563A.
Data Sheet	Data sheet of NOX-6-18
CoA	CoA of NOX-6-18
SDS	SDS of NOX-6-18

Smiles:	O=C(O)C=1OC=2C=CC(=CC2C1C)S(=O)(=O)NCCC=3C=CC=CC3


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