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Product Information:

Norbinaltorphimine dihydrochloride

Norbinaltorphimine dihydrochloride is a potent and selective κ opioid receptor antagonist.

Cat. No.: EX-A15304    Purity: >98%
Chemical
Chemical structure of Norbinaltorphimine dihydrochloride


For research only, Do not use for Human!

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Synonymsnor-Binaltorphimine dihydrochloride
Synonyms 2nor-BNI dihydrochloride
CAS No.113158-34-2
Purity>98%
FormulaC40H45Cl2N3O6
Mol Weight734.708
ColorLight yellow to gray
StateSolid
Solubilitysoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4°C, sealed storage, away from moisture; In solvent -20°C, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Birch PJ, et al. Norbinaltorphimine: antagonist profile at kappa opioid receptors. Eur J Pharmacol. 1987 Dec 15;144(3):405-8.

[2]. Flax SM, et al. Effect of norbinaltorphimine on ∆⁹-tetrahydrocannabinol (THC)-induced taste avoidance in adolescent and adult Sprague-Dawley rats. Psychopharmacology (Berl). 2015 Sep;232(17):3193-201.

[3]. Jackson KJ, et al. Effects of the kappa opioid receptor antagonist, norbinaltorphimine, on stress and drug-induced reinstatement of nicotine-conditioned place preference in mice. Psychopharmacology (Berl). 2013 Apr;226(4):763-8.

CoACoA of Norbinaltorphimine dihydrochloride
Smiles:C1CC1CN2CC[C@]34[C@@H]5C6=C(C[C@]3([C@H]2CC7=C4C(=C(C=C7)O)O5)O)C8=C(N6)[C@H]9[C@@]12CCN([C@@H]([C@@]1(C8)O)CC1=C2C(=C(C=C1)O)O9)CC1CC1.Cl.Cl

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