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Product Information:

NLRP3-IN-41

NLRP3-IN-41 administered at doses of 40 and 80 mg/kg through intragastric (i.g.) delivery over a span of 10 days, successfully alleviated the symptoms of colitis induced by DSS in both C57BL/6 and ICR mice.

Cat. No.: EX-A10113    Purity: >98%
Chemical
Chemical structure of NLRP3-IN-41


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg5953 weeks
250mg8253 weeks
500mgget quote3 weeks
1g13423 weeks


CAS No.1209698-02-1
Purity>98%
FormulaC22H22N2O4S2
Mol Weight442.551
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Yang F, et al. Identification and Validation of PKR as a Direct Target for the Novel Sulfonamide-Substituted Tetrahydroquinoline Nonselective Inhibitor of the NLRP3 Inflammasome. J Med Chem. 2024 Jun 10.

CoACoA of NLRP3-IN-41
Smiles:O=S(=O)(NC1=CC=C2C(=C1)N(CCC2)S(=O)(=O)C)C=3C=CC(=CC3)C=4C=CC=CC4

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