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Product Information:

NLRP3-IN-38

NLRP3-IN-38 (Compound 18) is an inhibitor for NOD-like receptor protein 3 (NLRP3), that inhibits NLRP3 inflammasome activation with an EC50 of 23 nM.

Cat. No.: EX-A13657    Purity: >98%
Chemical
Chemical structure of NLRP3-IN-38


For research only, Do not use for Human!

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CAS No.3033054-46-2
Purity>98%
FormulaC21H21F3N4O2
Mol Weight418.4122
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Donna A. A. W. HAYES, et al., Phthalazine derivatives useful as inhibitors of nod-like receptor protein 3. WO2024064245A1.

CoACoA of NLRP3-IN-38
Smiles:C[C@H]1CN(C[C@H]([C@@H]1O)C)C2=C3C=NC=CC3=C(N=N2)C4=CC=C(C=C4O)C(F)(F)F

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