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Product Information:

NLG919

RG 6078 (NLG-919 analogue, GDC-0919 analogue) is a a potent IDO1 inhibitor with IC50 of 38 nM.

Cat. No.: EX-A574    Purity: >98%
Chemical
Chemical structure of NLG919


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg300In-stock
500mg425In-stock
1g600In-stock
5g2350In-stock
10g3500In-stock
25gget quoteIn-stock


SynonymsNLG919 analogue
Synonyms 2GDC-0919 analogue
CAS No.1402836-58-1
Purity>98%
FormulaC18H22N2O
Mol Weight282.3801
Statesolid powder
SolubilitySoluble in DMSO, Ethanol
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Coletti, Alice et al. “Fragment-based approach to identify IDO1 inhibitor building blocks.” European journal of medicinal chemistry vol. 141 (2017): 169-177.

[2]. Peng, Yi-Hui et al. “Important Hydrogen Bond Networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Design Revealed by Crystal Structures of Imidazoleisoindole Derivatives with IDO1.” Journal of medicinal chemistry vol. 59,1 (2016): 282-93.

CoACoA of NLG919
Smiles:OC(CC1N2C=NC=C2C2=C1C=CC=C2)C1CCCCC1

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