NIBR-LTSi

NIBR-LTSi is a selective LATS kinase inhibitor and activates YAP signaling. NIBR-LTSi promotes proliferation, maintains stemness, and blocks differentiation. NIBR-LTSi accelerates liver regeneration, following partial and extended hepatectomy.


Cat. No.: EX-A9774	Purity: >98%

	Chemical structure of NIBR-LTSi

For research only, Do not use for Human!

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Purity	>98%
Formula	C18H20N4O
Mol Weight	308.3776

Reference:	[1]. Namoto K, et al. NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo. Cell Stem Cell. 2024 Apr 4;31(4):554-569.e17.
CoA	CoA of NIBR-LTSi

Smiles:	C1(NC2=CC=C(C=C2)O[C@H]3CNCCC3)=CC=NC4=C1C=CN4


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