NI-42

NI-42 (compound 13-d), a structurally orthogonal chemical probe for the BRPFs, is a biased, potent inhibitor of the BRD of the BRPFs (IC50s of BRPF1/2/3=7.9/48/260 nM.


Cat. No.: EX-A5675	Purity: >98%

	Chemical structure of NI-42

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	500	In-stock
200mg	700	In-stock
500mg	950	In-stock
1g	1350	In-stock

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CAS No.	1884640-99-6
Purity	>98%
Formula	C18H15N3O3S
Mol Weight	353.395
Color	Off-white to pink
State	solid powder
Solubility	Soluble in DMSO 100 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Igoe N, et al. Design of a Biased Potent Small Molecule Inhibitor of the Bromodomain and PHD Finger-Containing (BRPF) Proteins Suitable for Cellular and in Vivo Studies. J Med Chem. 2017 Jan 26;60(2):668-680.
CoA	CoA of NI-42


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