Neoeriocitrin

Neoeriocitrin is a Naringin analogue found in Drynaria Rhizome. Neoeriocitrin induces cells proliferation, differentiation, up-regulates type I collagen, osteocalcin, and key osteogenic markers, and increases ALP activity. Neoeriocitrin increases expression of Runx2, COL I, OCN and Beclin1. Neoeriocitrin inhibits phosphorylation of P38 mitogen-activated protein kinase, reduces acetylcholinesterase (AChE) activity, and increases choline acetyltransferase (ChAT) activity. Neoeriocitrin reduces apoptosis and induces autophagy. Neoeriocitrin can be used for the researches of osteoporosis and Alzheimer's disease.


Cat. No.: EX-A6775	Purity: >98%

	Chemical structure of Neoeriocitrin

For research only, Do not use for Human!

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CAS No.	13241-32-2
Purity	>98%
Formula	C27H32O15
Mol Weight	596.534
Color	White to off-white
State	solid powder
Solubility	Soluble in DMSO 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, protect from light; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Li L, et al. Comparison of neoeriocitrin and naringin on proliferation and osteogenic differentiation in MC3T3-E1. Phytomedicine. 2011;18(11):985-989. [2]. Wu Y, et al. Neoeriocitrin Targeting Beclin1 Deubiquitination and Autophagy in Osteogenic Differentiation of Human Dental Pulp Stem Cells. Adv Sci (Weinh). 2025;12(43):e04378. [3]. NISHIURA M, et al. Flavonoids in Citrus and related genera Part II. Isolation and identification of isonaringin and neoeriocitrin from Citrus[J]. Agricultural and Biological Chemistry, 1971, 35(11): 1683-1690. [4]. van der Meer JW, et al. Abstract!. Neth J Med. 2002;60(11):418.
CoA	CoA of Neoeriocitrin


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