Inhibitor Specialist 
Product Information:
| Cat. No.: EX-A3005 | Purity: >98% |
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| Chemical structure of Nec-1s |
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| Send PO to E-mail:[email protected]; or Fax:+86 020 81619670 |
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| Synonyms | Necrostatin 2 racemate |
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| CAS No. | 852391-15-2 |
| Purity | >98% |
| Formula | C13H12ClN3O2 |
| Mol Weight | 277.706 |
| State | solid powder |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
| Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Reference: | [1]. Meng, H., Wu, G., Zhao, X. et al. Discovery of a cooperative mode of inhibiting RIPK1 kinase. Cell Discov 7, 41 (2021). https://doi.org/10.1038/s41421-021-00278-x
[2]. Takahashi, N., et al. . Necrostatin-1 analogues: Critical issues on the specificity, activity and in vivo use in experimental disease models. Cell Death Dis. 3, e437 (2012). [3]. Huang, Z., et al. Necrostatin-1 rescues mice from lethal irradiation. Biochim. Biophys. Acta 1862(4), 850-856 (2016). |
| CoA | CoA of Nec-1s |
| Smiles: | CN1C(=O)NC(CC2=CNC3=C(Cl)C=CC=C23)C1=O |
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