NBOH-2C-CN hydrochloride

25CN-NBOH is a highly selective and brain penetrant 5-HT2A receptor agonist (Ki value of 1.3 nM; EC50 value of 2.1 nM). Moreover, 25CN-NBOH was behaviorally active in two mouse models of hallucinogenic effects.


Cat. No.: EX-A5074	Purity: >98%

	Chemical structure of NBOH-2C-CN hydrochloride

For research only, Do not use for Human!

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Synonyms	25CN-NBOH hydrochloride
CAS No.	1539266-32-4
Purity	>98%
Formula	C18H21ClN2O3
Mol Weight	348.824
State	solid powder
Solubility	Soluble in DMSO and water
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Hansen M, et al. Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT2A/2C agonists. ACS Chem Neurosci. 2014 Mar 19;5(3):243-9. [2]. Fantegrossi WE, et al. Hallucinogen-like effects of 2-([2-(4-cyano-2,5-dimethoxyphenyl) ethylamino]methyl)phenol (25CN-NBOH), a novel N-benzylphenethylamine with 100-fold selectivity for 5-HT₂A receptors, in mice. Psychopharmacology (Berl). 2015 Mar;232(6):1039-47. [3]. Jensen AA, et al. Detailed Characterization of the In Vitro Pharmacological and Pharmacokinetic Properties of N-(2-Hydroxybenzyl)-2,5-Dimethoxy-4-Cyanophenylethylamine (25CN-NBOH), a Highly Selective and Brain-Penetrant 5-HT2A Receptor Agonist. J Pharmacol Exp Ther. 2017 Jun;361(3):441-453.
CoA	CoA of NBOH-2C-CN hydrochloride

Smiles:	OC(C=CC=C2)=C2CNCCC1=C(OC)C=C(C#N)C(OC)=C1.Cl


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