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Product Information:

NBI-921352

Zandatrigine (NBI-921352) is a sodium channel protein type 8 subunit alpha (Scn8α) blocker.

Cat. No.: EX-A8340    Purity: >98%
Chemical
Chemical structure of NBI-921352


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg608in_stock
500mg954in_stock
1g1546in_stock


SynonymsZandatrigine
Synonyms 2XEN901
CAS No.2154406-04-7
Purity>98%
FormulaC22H25FN4O2S2
Mol Weight460.588
ColorWhite to light yellow
Statesolid powder
SolubilityDMSO : 125 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Johnson JP, Focken T, Khakh K, et al. NBI-921352, a first-in-class, NaV1.6 selective, sodium channel inhibitor that prevents seizures in Scn8a gain-of-function mice, and wild-type mice and rats. Elife. 2022;11:e72468. Published 2022 Mar 2. doi:10.7554/eLife.72468

[2]. International Nonproprietary Names for Pharmaceutical Substances (INN). WHO Drug Information, Vol. 36, No. 2, 2022.

CoACoA of NBI-921352
Smiles:CN([C@@H]1CN(CC1)CC2=CC=CC=C2)C3=C(C=C(C(F)=C3)S(NC4=CSC=N4)(=O)=O)C

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