Nampt-IN-5

Nampt-IN-5 is a potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitor. Nampt-IN-5 also inhibits CYP3A4 activity and has cellular IC50s of 0.7 nM and 3.9 nM against A2780 and COR-L23, respectively.


Cat. No.: EX-A5242	Purity: >98%

	Chemical structure of Nampt-IN-5

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	550	In-stock
25mg	750	In-stock
50mg	1150	In-stock
100mg	1850	In-stock
200mg	2950	In-stock

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CAS No.	2380013-17-0
Purity	>98%
Formula	C25H25N5O2
Mol Weight	427.4983
Color	White to off-white
State	solid powder
Solubility	Soluble in DMSO 50 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Palacios DS, et al. Scaffold Morphing Identifies 3-Pyridyl Azetidine Ureas as Inhibitors of Nicotinamide Phosphoribosyltransferase (NAMPT).ACS Med Chem Lett. 2019 Oct 10;10(11):1524-1529.
CoA	CoA of Nampt-IN-5

Smiles:	O=C(N1CC(C2=CC=CN=C2)C1)NC3=CC=C(CN4C5=CC=CC=C5N=C4OCC)C=C3


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