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Product Information:

Nampt-IN-16

Nampt-IN-16 (Compound 9a) is an orally active NAMPT inhibitor with an IC50 of 0.15 μM. Nampt-IN-16 can reduce intracellular NAD+ and ATP levels. Nampt-IN-16 can inhibit the proliferation, migration, and invasion, induce cell cycle arrest and apoptosis, and alter cellular metabolism of gastric cancer cells. Nampt-IN-16 can be used in the research of tumors such as gastric cancer.

Cat. No.: EX-A14025    Purity: >98%
Chemical
Chemical structure of Nampt-IN-16


For research only, Do not use for Human!

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CAS No.3077970-44-3
Purity>98%
FormulaC25H25FN4O3
Mol Weight448.4894
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Zhang S, et al. Novel Carbamate-Based o-aminobenzamide Derivatives as Potent Antigastric Carcinoma Agents via Disrupting NAD+ Salvage Synthesis. J Med Chem. 2025 Jun 12;68(11):10738-10756.

CoACoA of Nampt-IN-16
Smiles:O=C(NC1=CC=C(CNC(C2=C(N3CCCC3)C=CC(F)=C2)=O)C=C1)OCC4=CC=CN=C4

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