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Product Information:

N-Me-L-Ala-maytansinol

N-Me-L-Ala-maytansinol is a hydrophobic, cell permeable payload used for making antibody-drug conjugate (ADC).

Cat. No.: EX-A4368    Purity: >98%
Chemical
Chemical structure of N-Me-L-Ala-maytansinol


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg2400In-stock
1g3800In-stock


SynonymsAP3 Intermidate 1
Synonyms 2Maytansinol-Ala
CAS No.77668-69-0
Purity>98%
FormulaC32H44ClN3O9
Mol Weight650.159
Colorwhite to off-white
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Nittoli T, et al. Antibody drug conjugates of cleavable amino-alkyl and aryl maytansinoids. Bioorg Med Chem. 2018 May 15;26(9):2271-2279.

CoACoA of N-Me-L-Ala-maytansinol
Smiles:C[C@]12[C@H]([C@@H]([C@](O3)([H])C[C@]([C@](/C=C/C=C(C)/CC4=CC(N(C)C(C[C@]2([H])OC([C@H](C)NC)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1

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