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Product Information:

MSDC-0602 potassium

MSDC-0602 is an insulin sensitizer potentially for the treatment of diabetes (metabolic modulator).

Cat. No.: EX-A5499    Purity: >98%
Chemical
Chemical structure of MSDC-0602 potassium


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
10mg385In-stock
25mg585In-stock
50mg785In-stock
100mg1085In-stock
200mg1600In-stock


CAS No.1314533-27-1
Purity>98%
FormulaC19H16KNO5S
Mol Weight409.497
Color White to off-white
Statesolid powder
SolubilitySoluble in DMSO 250 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4°C, sealed storage, away from moisture; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. McCommis KS, et al. Targeting the Mitochondrial Pyruvate Carrier Attenuates Fibrosis in a Mouse Model of Nonalcoholic Steatohepatitis. Hepatology. 2016 Dec 27. doi: 10.1002/hep.29025. [Epub ahead of print] PubMed PMID: 28027586.

[2]. Fukunaga T, et al. An insulin-sensitizing thiazolidinedione, which minimally activates PPARγ, does not cause bone loss. J Bone Miner Res. 2015 Mar;30(3):481-8. doi: 10.1002/jbmr.2364. PubMed PMID: 25257948; PubMed Central PMCID: PMC4472363.

[3].Chen Z, et al. Insulin resistance and metabolic derangements in obese mice are ameliorated by a novel peroxisome proliferator-activated receptor γ-sparing thiazolidinedione. J Biol Chem. 2012 Jul 6;287(28):23537-48. doi: 10.1074/jbc.M112.363960. PubMed PMID: 22621923; PubMed Central PMCID: PMC3390629.

[4]. Colca JR, et al. Identification of a mitochondrial target of thiazolidinedione insulin sensitizers (mTOT)--relationship to newly identified mitochondrial pyruvate carrier proteins. PLoS One. 2013 May 15;8(5):e61551. doi: 10.1371/journal.pone.0061551. PubMed PMID: 23690925; PubMed Central PMCID: PMC3655167.
CoACoA of MSDC-0602 potassium

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