MSA-2 dimer

MSA-2 dimer is a selective, orally active non-nucleotide STING agonist (Kd=145 μM) with long-term antitumor and immunogenic activity. MSA-2 dimer is bound to STING as a non-covalent dimer exhibiting higher permeability than cyclic dinucleotide .


Cat. No.: EX-A8610	Purity: >98%

	Chemical structure of MSA-2 dimer

For research only, Do not use for Human!

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CAS No.	2377881-92-8
Purity	>98%
Formula	C29H28O8S2
Mol Weight	568.658
Color	White to yellow
State	solid powder
Solubility	DMSO : 70 mg/mL
Shelf Life	>3 years if stored properly
Storage	4°C, sealed storage, away from moisture and light
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Pan BS, et al. An orally available non-nucleotide STING agonist with antitumor activity. Science. 2020;369(6506):eaba6098.
CoA	CoA of MSA-2 dimer

Smiles:	O=C(CCC(C1=CC2=C(C=C(C(CCCC3=CC4=C(C=C3OC)SC(C(CCC(O)=O)=O)=C4)=C2)OC)S1)=O)O


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