background


Product Information:

MS177

MS177 is a potent and selective EZH2 degarder (PROTAC) based on EZH2 inhibitor C24 with CRBN ligand pomalidomide with DC50 of 0.2 uM in EOL-1 cells.

Cat. No.: EX-A6480    Purity: >98%
Chemical
Chemical structure of MS177


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg785Inquire
100mg1185Inquire
250mg1685Inquire
500mg2385Inquire
1g3285Inquire
5g8850Inquire


CAS No.2225938-86-1
Purity>98%
FormulaC48H55N11O8
Mol Weight914.0192
ColorLight yellow to yellow
Statesolid powder
SolubilitySoluble in DMSO 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Wang, Jun et al. EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis. Nature cell biology vol. 24,3 (2022): 384-399.

CoACoA of MS177

KEYWORDS: buy MS177 | MS177 supplier | purchase | cost | manufacturer | order | distributor | buy 2225938-86-1 | 2225938-86-1 supplier