MS-II-124

MS-II-124 is an effective and selective NLRP3 inhibitor (IC50=0.12 μM) with anti-inflammatory and immunomodulatory activities, which can be used in the research of acute lung injury (ALI)/acute respiratory distress syndrome (ARDS).


Cat. No.: EX-A13367	Purity: >98%

	Chemical structure of MS-II-124

For research only, Do not use for Human!

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CAS No.	3037332-85-4
Purity	>98%
Formula	C28H28ClFN2O4S
Mol Weight	543.049
Color	White to off-white
State	Solid
Solubility	DMSO : 35 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Xu Y, et al. Characterization of a small molecule inhibitor of the NLRP3 inflammasome and its potential use for acute lung injury[J]. Bioorganic Chemistry, 2024: 107562.
CoA	CoA of MS-II-124

Smiles:	ClC1=CC=C(OCCC)C(CN(CCC2=CC=C(S(=O)(NCC#C)=O)C=C2)C(C3=CC=C(F)C=C3)=O)=C1


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