MRTX849 acid

MRTX849 acid, a derivative of MRTX849, can be used in the synthesis of PROTAC LC-2. LC-2 is a potent and first-in-class PROTAC capable of degrading endogenous KRAS G12C (DC50s between 0.25 and 0.76 μM).


Cat. No.: EX-A5368	Purity: >98%

	Chemical structure of MRTX849 acid

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	985	In-stock
25mg	1985	In-stock
50mg	3200	In-stock
100mg	4800	In-stock
500mg	get quote	In-stock
1g	get quote	In-stock

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CAS No.	2561529-96-0
Purity	>98%
Formula	C34H37ClFN7O4
Mol Weight	662.153
Color	Light yellow to yellow
State	solid powder
Solubility	Soluble in DMSO 130 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20°C, protect from light, stored under nitrogen; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Bond MJ, et al. Targeted Degradation of Oncogenic KRASG12C by VHL-Recruiting PROTACs. ACS Cent Sci. 2020;6(8):1367-1375.
CoA	CoA of MRTX849 acid


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