background


Product Information:

MRTX1719

MRTX1719 is a synthetic lethal inhibitor of the PRMT5/MTA complex and selectively inhibits PRMT5 activity.

Cat. No.: EX-A5505    Purity: >99% ee:>99%
Chemical
Chemical structure of MRTX1719


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg568in_stock
250mg1077in_stock
500mg1645in_stock
1g2772in_stock
2g4289in_stock


Synonyms(R)-MRTX-1719
Synonyms 2R-MRTX-1719
CAS No.2630904-45-7
Purity>99% ee:>99%
FormulaC23H18ClFN6O2
Mol Weight464.879
ColorWhite to light yellow
Statesolid powder
SolubilitySoluble in DMSO 100 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Smith, Christopher R et al. Fragment-Based Discovery of MRTX1719, a Synthetic Lethal Inhibitor of the PRMT5•MTA Complex for the Treatment of MTAP-Deleted Cancers. Journal of medicinal chemistry vol. 65,3 (2022): 1749-1766.

CoACoA of MRTX1719
Smiles:CN1N=CC(C2=CC=C(C(NN=C3CN)=O)C3=C2)=[C@]1[C@]4=C(C#N)C(OC5CC5)=CC(Cl)=C4F

KEYWORDS: buy MRTX1719 | MRTX1719 supplier | purchase | cost | manufacturer | order | distributor | buy 2630904-45-7 | 2630904-45-7 supplier