MRT-14

MRT-14 is a potent antagonist of Smo. Smo is the major component involved in signal transduction of the Hedgehog (Hh) morphogens. MRT-14 has the potential for the research of several types of cancers linked to abnormal Hh signaling.


Cat. No.: EX-A5788	Purity: >98%

	Chemical structure of MRT-14

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	550	In-stock
250mg	850	In-stock
500mg	1250	In-stock
1g	1850	In-stock
5g	6475	In-stock

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CAS No.	1263131-83-4
Purity	>98%
Formula	C24H24N4O5
Mol Weight	448.4712
Color	Off-white to light yellow
State	solid powder
Solubility	Soluble in DMSO 100 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder 4°C, protect from light; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Manetti F, et al. Virtual screening-based discovery and mechanistic characterization of the acylthiourea MRT-10 family as smoothened antagonists. Mol Pharmacol. 2010;78(4):658-665.
CoA	CoA of MRT-14


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