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Product Information:

MP-1

MP-1 is a potent Fumarate hydratase-dependent hit. MP-1 engages an array of functional cysteines, including one lying in the Zn-finger domain of the tRNA methyltransferase enzyme TRMT1. MP-1 causes fumarate hydratase-dependent synthetic lethality in a metastatic hereditary leiomyomatosis and renal cell carcinoma cell line .

Cat. No.: EX-A15500    Purity: >98%
Chemical
Chemical structure of MP-1


For research only, Do not use for Human!

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CAS No.2035018-15-4
Purity>98%
FormulaC15H17NO3S
Mol Weight291.365
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Perez M, et al. Conditional Covalent Lethality Driven by Oncometabolite Accumulation. ACS Chem Biol. 2022 Oct 21;17(10):2789-2800.

CoACoA of MP-1
Smiles:O=C(C=CC=1OC=CC1)NCCC=2SC(=CC2)C(O)C

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