Moracin O

Moracin O is a 2-arylbenzofuran isolated from the Morus alba Linn. . Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin O reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin O has neuroprotective and anti-inflammatory effects.


Cat. No.: EX-A12061	Purity: >98%

	Chemical structure of Moracin O

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	350	In-stock
25mg	700	In-stock
50mg	1120	In-stock
100mg	1750	In-stock
250mg	3560	In-stock
500mg	5700	In-stock

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CAS No.	123702-97-6
Purity	>98%
Formula	C19H18O5
Mol Weight	326.3432
Color	White to light yellow
State	solid
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, protect from light; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Hak Ju Lee, et al. Inhibitory effect of 2-arylbenzofurans from the Mori Cortex Radicis (Moraceae) on oxygen glucose deprivation (OGD)-induced cell death of SH-SY5Y cells. Arch Pharm Res. 2011 Aug;34(8):1373-80. [2]. Yan Xia, et al. HIF-1α inhibitors: synthesis and biological evaluation of novel moracin O and P analogues. Eur J Med Chem. 2011 Jun;46(6):2386-96. [3]. Besse Hardianti, et al. Anti-inflammatory compounds moracin O and P from Morus alba Linn. (Sohakuhi) target the NF‑κB pathway. Mol Med Rep. 2020 Dec;22(6):5385-5391.
CoA	CoA of Moracin O

Smiles:	[C@@](C)(C)(O)[C@H]1CC=2C(=CC3=C(C2)C=C(O3)C4=CC(O)=CC(O)=C4)O1


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