MMP2-IN-2

MMP2-IN-2 (compound 42) is a potent and selective MMP-2 (matrix metalloproteinases) inhibitor, with an IC50 of 4.2 μM. MMP2-IN-2 also shows inhibitory activity against MMP-13, MMP-9 and MMP-8, with IC50 values of 12, 23.3, and 25 μM, respectively.


Cat. No.: EX-A10992	Purity: >98%

	Chemical structure of MMP2-IN-2

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
1g	550	In-stock
5g	1920	In-stock
10g	3420	In-stock

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CAS No.	1772-39-0
Purity	>98%
Formula	C13H8N4O4
Mol Weight	284.227
Color	Yellow to brown
State	Solid
Solubility	DMSO : 7.14 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4℃, protect from light; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Laghezza A, et al. Virtual screening identification and chemical optimization of substituted 2-arylbenzimidazoles as new non-zinc-binding MMP-2 inhibitors. Bioorg Med Chem. 2020 Feb 1;28(3):115257.
CoA	CoA of MMP2-IN-2

Smiles:	O=[N+](C1=CC=C(C2=NC3=CC=C([N+]([O-])=O)C=C3N2)C=C1)[O-]


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