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Product Information:

MMH1

MMH1 is a novel BRD4 molecular glue degrader that functions by recruiting the CUL4 and DCAF16 ligases to the second bromodomain of BRD4 (BRD4BD2).

Cat. No.: EX-A11425    Purity: >98%
Chemical
Chemical structure of MMH1


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg1285Inquire
500mgget quoteInquire
1gget quoteInquire


CAS No.3079093-16-3
Purity>98%
FormulaC26H29N5O3S
Mol Weight491.605
Color White to off-white
StateSolid
SolubilityDMSO : 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years; 4℃, 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Yen-Der Li, et al. Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders. bioRxiv. 2023 Feb 15:2023.02.14.528208.

CoACoA of MMH1
Smiles:CC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)OC(C)(C)C)C4=CC=C(C=C4)NC(=O)C=C)C

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