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Product Information:

MMAF-OMe

MMAF-Ome, an antitubulin agent, is also an ADC cytotoxin. MMAF-Ome inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4-) cell lines, respectively.

Cat. No.: EX-A6232    Purity: >98%
Chemical
Chemical structure of MMAF-OMe


For research only, Do not use for Human!

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CAS No.863971-12-4
Purity>98%
FormulaC40H67N5O8
Mol Weight745.9887
Color Off-white to light yellow
Statesolid powder
SolubilitySoluble in DMSO ? 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Currier NV, et al. Targeted Drug Delivery with an Integrin-Binding Knottin-Fc-MMAF Conjugate Produced by Cell-Free Protein Synthesis. Mol Cancer Ther. 2016 Jun;15(6):1291-300

CoACoA of MMAF-OMe

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