MLN0905

MLN0905 is a potent, orally active Polo-like kinase 1 (PLK1) inhibitor. MLN0905 has inhibitory potency against PLK1 with an IC50 value of 2 nM. MLN0905 can be used for the research of cancer.


Cat. No.: EX-A2105	Purity: >98%

	Chemical structure of MLN0905

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	850	In-stock
500mg	1380	In-stock
1g	2350	In-stock
5g	6850	Inquire

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CAS No.	1228960-69-7
Purity	>98%
Formula	C24H25F3N6S
Mol Weight	486.556
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Duffey MO, et al. Discovery of a potent and orally bioavailable benzolactam-derived inhibitor of Polo-like kinase 1 (MLN0905). J Med Chem. 2012 Jan 12;55(1):197-208. [2]. Shi JQ, et al. MLN0905, a small-molecule plk1 inhibitor, induces antitumor responses in human models of diffuse large B-cell lymphoma. Mol Cancer Ther. 2012 Sep;11(9):2045-53.
CoA	CoA of MLN0905

Smiles:	CN(C)CCCC1=CN=C(C)C(NC2=NC3=C(CC(=S)NC4=C3C=CC(=C4)C(F)(F)F)C=N2)=C1


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