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Product Information:

MLN 4924

MLN 4924 Pevonedistat is a potent and selective NEDD8-activating enzyme (NAE) inhibitor with an IC50 of 4.7 nM

Cat. No.: EX-A1472    Purity: >98%
Chemical
Chemical structure of MLN 4924


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg600In-stock
250mg950In-stock
500mg1550In-stock
1g2450In-stock
5g6800Inquire
10g9800Inquire


SynonymsPevonedistat
Synonyms 2MLN4924
CAS No.905579-51-3
Purity>98%
FormulaC21H25N5O4S
Mol Weight443.519
Statesolid powder
Solubilitysoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Soucy TA, et al. An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer. Nature. 2009 Apr 9;458(7239):732-6.

CoACoA of MLN 4924
Smiles:NS(=O)(=O)OC[C@@H]1C[C@H](C[C@@H]1O)N1C=CC2=C(N[C@H]3CCC4=C3C=CC=C4)N=CN=C12

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