ML67-33

ML67-33 is a selective activator of temperature- and mechano-sensitive K2P channels. ML67-33 rapidly and reversibly affects K2P2.1 (TREK-1) with EC50s of 36.3 μM and 9.7 μM in cell-free and HEK293 cells, respectively.


Cat. No.: EX-A9403	Purity: >98%

	Chemical structure of ML67-33

For research only, Do not use for Human!

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CAS No.	1443290-89-8
Purity	>98%
Formula	C18H17Cl2N5
Mol Weight	374.267

Reference:	[1]. Bagriantsev SN, et al. A high-throughput functional screen identifies small molecule regulators of temperature- and mechano-sensitive K_2P channels. ACS Chem Biol. 2013 Aug 16;8(8):1841-51.
CoA	CoA of ML67-33

Smiles:	CC1(C)C2=C(C=CC(Cl)=C2)N(CCC3=NN=NN3)C4=CC=C(Cl)C=C14


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