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Product Information:

ML-211

ML-211 is a carbamate-based dual inhibitor of LYPLA1 (IC50 = 17 nM) and the related LYPLA2 (IC50 = 30 nM).

Cat. No.: EX-A4772    Purity: 98+%
Chemical
Chemical structure of ML-211


For research only, Do not use for Human!

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CAS No.2205032-89-7
Purity98+%
FormulaC25H30N4O2
Mol Weight418.5313
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Martin, B.R., and Cravatt, B.F. Large-scale profiling of protein palmitoylation in mammalian cells. Nat. Methods 6(2), 135-138 (2009).

[2]. Dekker, F.J., Rocks, O., Vartak, N., et al. Small-molecule inhibition of APT1 affects Ras localization and signaling. Nature Chemical Biology 6, 449-456 (2010).
CoACoA of ML-211
Smiles:CC(C)(C)C1CCN(C(N2N=C(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)C=N2)=O)CC1

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