ML-210

ML-210 is a selective and covalent glutathione peroxidase 4 (GPX4) inhibitor with an EC50 of 30 nM. ML-210 binds the GPX4 selenocysteine residue. ML-210 has anti-cancer activity.


Cat. No.: EX-A3516	Purity: >98%

	Chemical structure of ML-210

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	350	In-stock
100mg	500	In-stock
250mg	785	In-stock
500mg	1185	In-stock
1g	1585	In-stock
2g	2500	In-stock

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CAS No.	1360705-96-9
Purity	>98%
Formula	C22H20Cl2N4O4
Mol Weight	475.325
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. John K. Eaton, et al. Targeting a Therapy-Resistant Cancer Cell State Using Masked Electrophiles as GPX4 Inhibitors. Biorxiv. 2018. [2]. Weïwer M, et al. Development of small-molecule probes that selectively kill cells induced to express mutant RAS. Bioorg Med Chem Lett. 2012 Feb 15;22(4):1822-6. /p>
CoA	CoA of ML-210

Smiles:	O=C(N1CCN(C(C2=CC=C(Cl)C=C2)C3=CC=C(Cl)C=C3)CC1)C4=NOC(C)=C4[N+]([O-])=O


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