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Product Information:

MK2-IN-3

MK2 inhibitor III is a potent and selective inhibitor of MK-2 with an IC50 value of 8.5 nM. MK2 inhibitor III was found to be effective in reducing TNF-α production in both U937 cells and in vivo.

Cat. No.: EX-A5291    Purity: >98%
Chemical
Chemical structure of MK2-IN-3


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg485In-stock
100mg685In-stock
200mg985In-stock
500mg1585In-stock


SynonymsMK2 Inhibitor III
CAS No.724711-21-1
Purity>98%
FormulaC21H16N4O
Mol Weight340.3779
ColorOff-white to gray
Statesolid powder
SolubilitySoluble in DMSO 62.5 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4°C, protect from light; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Anderson DR, et, al. Pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2). J Med Chem. 2007 May 31;50(11):2647-54.
CoACoA of MK2-IN-3
Smiles:O=C1C2=C(NC(C3=CC(C4=CC5=CC=CC=C5N=C4)=NC=C3)=C2)CCN1

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