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Product Information:

MK-5108

MK-5108 is a highly potent and specific inhibitor of Aurora A kinase with an IC50 value of 0.064 nM.

Cat. No.: EX-A093    Purity: >98%
Chemical
Chemical structure of MK-5108


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg446in_stock
250mg889in_stock
500mg1430in_stock
1g2240in_stock
2g3701in_stock
3g4285in_stock


SynonymsVX-689
CAS No.1010085-13-8
Purity>98%
FormulaC22H21ClFN3O3S
Mol Weight461.937
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 3 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Shimomura T, et al. MK-5108, a highly selective Aurora-A kinase inhibitor, shows antitumor activity alone and in combination with docetaxel. Mol Cancer Ther. 2010 Jan;9(1):157-66.

CoACoA of MK-5108
Smiles:OC(=O)[C@@]1(CC2=NC(NC3=NC=CS3)=CC=C2)CC[C@@H](CC1)OC1=CC=CC(Cl)=C1F

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