MK-3207

MK-3207 is an orally active, highly selective and species-specific CGRP receptor antagonist (for human CGRP receptor: IC50=0.12 nM; Ki=0.024 nM). MK-3207 can be used for migraine studies.


Cat. No.: EX-A11218	Purity: >98%

	Chemical structure of MK-3207

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
500mg	get quote	In-stock
1g	get quote	In-stock

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CAS No.	957118-49-9
Purity	>98%
Formula	C31H29F2N5O3
Mol Weight	557.5905
Color	Off-white to light yellow
State	solid
Solubility	DMSO : ? 150 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, stored under nitrogen; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Salvatore CA, Moore EL, Calamari A, Pharmacological properties of MK-3207, a potent and orally active calcitonin gene-related peptide receptor antagonist. J Pharmacol Exp Ther. 2010 Apr;333(1):152-60.
CoA	CoA of MK-3207

Smiles:	O=C1C2(NC[C@@H](C3=CC(F)=CC(F)=C3)N1CC(NC4=CC5=C(C[C@@]6(C(NC7=C6C=CC=N7)=O)C5)C=C4)=O)CCCC2


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