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Product Information:

MK-28

MK-28 is a potent and selective PERK activator. MK-28 exhibits remarkable pharmacokinetic properties and high BBB penetration in mice[1].

Cat. No.: EX-A14675    Purity: >98%
Chemical
Chemical structure of MK-28


For research only, Do not use for Human!

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CAS No.864388-65-8
Purity>98%
FormulaC24H20N4O2
Mol Weight396.4412
ColorLight yellow to yellow
StateSolid
Solubilitysoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃, 3 years; 4℃, 2 years; In solvent -20℃, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Javier Ganz, et al. A novel specific PERK activator reduces toxicity and extends survival in Huntington's disease models. Sci Rep. 2020 Apr 23;10(1):6875.

CoACoA of MK-28
Smiles:CN(C1=NC(=CC(=N1)C2=CC=CC=C2)C3=CC=CC=C3)/N=C/C4=CC(=C(C=C4)O)O

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