MK-0591

Quiflapon (MK-591) is a selective and specific 5-lipoxygenase-activating protein (FLAP) inhibitor with an IC50 of 1.6 nM in a FLAP binding assay. Quiflapon induces cell apoptosis.


Cat. No.: EX-A5139	Purity: >98%

	Chemical structure of MK-0591

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	485	In-stock
250mg	885	In-stock
500mg	1485	In-stock
1g	2285	In-stock
2g	3800	In-stock
5g	get quote	In-stock

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Synonyms	Quiflapon
CAS No.	136668-42-3
Purity	>98%
Formula	C34H35ClN2O3S
Mol Weight	587.171
Color	White to off-white
State	solid powder
Solubility	Soluble in DMSO ? 50 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Brideau C, et al. Pharmacology of MK-0591 (3-[1-(4-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-yl-methoxy)- indol-2-yl]-2,2-dimethyl propanoic acid), a potent, orally active leukotriene biosynthesis inhibitor. Can J Physiol Pharmacol. 1992 Jun;70(6):799-807. [2]. Park MS, et al. 5-Lipoxygenase-activating protein (FLAP) inhibitor MK-0591 prevents aberrant alveolarization in newborn mice exposed to 85% oxygen in a dose- and time-dependent manner. Lung. 2011 Feb;189(1):43-50
CoA	CoA of MK-0591


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