Miro1 Reducer

Miro1 Reducer is a small molecule that can repair this defect of Miro1 in Parkinson's disease (PD) fibroblasts. Miro1 Reducer reduces the delayed mitophagy phenotype in PD fibroblasts. Miro1 Reducer reduces Miro1 protein levels in dose-dependent manner (IC50 = 7.8 mM).


Cat. No.: EX-A8918	Purity: >98%

	Chemical structure of Miro1 Reducer

For research only, Do not use for Human!

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CAS No.	2624336-91-8
Purity	>98%
Formula	C20H17ClFN7O
Mol Weight	425.847
Color	Off-white to yellow
State	Solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, sealed storage, away from moisture; In solvent -20℃, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Hsieh CH, et al. Miro1 Marks Parkinson's Disease Subset and Miro1 Reducer Rescues Neuron Loss in Parkinson's Models. Cell Metab. 2019 Dec 3;30(6):1131-1140.e7.
CoA	CoA of Miro1 Reducer

Smiles:	O=C(NC1=CC(F)=CC=C1)NC2=CC=C(NC3=NC=NC(N4C=NC=C4)=C3)C=C2.Cl


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