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Product Information:

MIK665

MIK665 (S-64315) is a special Mcl-1 inhibitor with an IC50 of 1.81 nM.

Cat. No.: EX-A2912    Purity: >98%
Chemical
Chemical structure of MIK665


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg880in_stock
100mg1263in_stock
250mg1917in_stock
500mg2611in_stock
1g4424in_stock
2g6222in_stock


SynonymsS-64315
CAS No.1799631-75-6
Purity>98%
FormulaC47H44ClFN6O6S
Mol Weight875.405
Statesolid powder
SolubilityDMSO >100mg/mL; Insoluble in water
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Mukherjee N, et al. Simultaneously Inhibiting BCL2 and MCL1 Is a Therapeutic Option for Patients with Advanced Melanoma. Cancers (Basel). 2020;12(8):2182. Published 2020 Aug 5.

[2]. Zoltán SZLÁVIK, et al. New hydroxyester derivatives, a process for their preparation and pharmaceutical compositions containing them. WO2016207225A1.

CoACoA of MIK665
Smiles:COC1=CC=CC=C1C1=NC(COC2=C(C[C@@H](OC3=C4C(SC(=C4C4=C(C)C(Cl)=C(OCCN5CCN(C)CC5)C=C4)C4=CC=C(F)C=C4)=NC=N3)C(O)=O)C=CC=C2)=CC=N1

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