MID-1

MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction. MID-1 disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake.


Cat. No.: EX-A7550	Purity: >98%

	Chemical structure of MID-1

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	600	In-stock
100mg	850	In-stock
200mg	1385	In-stock
500mg	1985	In-stock
1g	2685	In-stock

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CAS No.	312608-54-1
Purity	>98%
Formula	C12H11N3O4S
Mol Weight	293.298
Color	Orange to red
State	solid powder
Solubility	DMSO : 31.25 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Lee H, et, al. MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) Interaction Disruptor Sensitizes Insulin Signaling in Skeletal Muscle. J Biol Chem. 2016 Dec 23;291(52):26627-26635.
CoA	CoA of MID-1


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