MGCD0103

Mocetinostat (MGCD0103) is a potent, orally active and isotype-selective HDAC (Class I/IV) inhibitor with IC50s of 0.15, 0.29, 1.66 and 0.59 μM for HDAC1, HDAC2, HDAC3 and HDAC11, respectively. Mocetinostat shows no inhibition on HDAC4, HDAC5, HDAC6, HDAC7, or HDAC8.


Cat. No.: EX-A049	Purity: >98%

	Chemical structure of MGCD0103

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
1g	480	In-stock
2g	850	In-stock
5g	1650	In-stock
10g	2800	In-stock
25g	4800	In-stock
50g	7800	In-stock

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Synonyms	Mocetinostat
CAS No.	726169-73-9
Purity	>98%
Formula	C23H20N6O
Mol Weight	396.4445
Color	white to off-white
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Fournel M, et al. MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo. Mol Cancer Ther. 2008 Apr;7(4):759-68. [2]. Cai J, et al. The Effect of MGCD0103 on CYP450 Isoforms Activity of Rats by Cocktail Method. Biomed Res Int. 2015;2015:517295.
CoA	CoA of MGCD0103

Smiles:	NC1=CC=CC=C1NC(=O)C1=CC=C(CNC2=NC=CC(=N2)C2=CC=CN=C2)C=C1


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