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Product Information:

Methylbiocin

Methylbiocin is an ATP competitive inhibitor for human CMG helicase with an IC50 of 59 µM. Methylbiocin exhibits potential in cancer research.

Cat. No.: EX-A13212    Purity: >98%
Chemical
Chemical structure of Methylbiocin


For research only, Do not use for Human!

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1gget quote


CAS No.23370-12-9
Purity>98%
FormulaC36H40N2O11
Mol Weight676.7096
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Xiang S, et al., Identification of ATP-Competitive Human CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function. Mol Cancer Ther. 2024 Jul 10.

CoACoA of Methylbiocin
Smiles:OC=1C=2C(=C(C)C(O[C@H]3[C@H](O)[C@H](OC(=O)C=4NC(C)=CC4)[C@@H](OC)C(C)(C)O3)=CC2)OC(=O)C1NC(=O)C5=CC(CC=C(C)C)=C(O)C=C5

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