methoctramine tetrahydrochloride hemihydrate

Methoctramine tetrahydrochloride is a potent and cardioselectivity antagonist of M2 muscarinic receptor. Methoctramine tetrahydrochloride can inhibit Muscarine (HY-121404)-induced bradycardia in vivo. Methoctramine tetrahydrochloride can be used in the study of cardiovascular diseases .


Cat. No.: EX-A17426	Purity: >98%

	Chemical structure of methoctramine tetrahydrochloride hemihydrate

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	498	In-stock
25mg	812	In-stock
50mg	1248	In-stock
100mg	1990	In-stock

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CAS No.	104807-46-7
Purity	>98%
Formula	C36H63ClN4O2
Mol Weight	619.364
Color	White to off-white
State	Solid
Solubility	H2O : ? 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, sealed storage, away from moisture
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1].Jaiswal N, et, al. Methoctramine, a cardioselective antagonist: muscarinic receptor mediating prostaglandin synthesis in isolated rabbit heart. Eur J Pharmacol. 1991 Jan 3;192(1):63-70. [2].Watson N, et, al. Actions of methoctramine, a muscarinic M2 receptor antagonist, on muscarinic and nicotinic cholinoceptors in guinea-pig airways in vivo and in vitro. Br J Pharmacol. 1992 Jan;105(1):107-12. [3].Wess J, et, al. Methoctramine selectively blocks cardiac muscarinic M2 receptors in vivo. Naunyn Schmiedebergs Arch Pharmacol. 1988 Sep;338(3):246-9.
CoA	CoA of methoctramine tetrahydrochloride hemihydrate

Smiles:	Cl.O(C=1C=CC=CC1CNCCCCCCNCCCCCCCCNCCCCCCNCC=2C=CC=CC2OC)C


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