MeSel

MeSeI exhibits weak inhibitory activity against monoamine oxidases MAO-A and MAO-B, with IC50 values of 198.8 µM. It modulates dopamine receptor D2 (dopamine receptorD2) and norepinephrine receptors α2, β1 (norepinephrine receptor α2, β1), displaying antidepressant-like effects in mice. Additionally, MeSeI is orally active.


Cat. No.: EX-A11484	Purity: >98%

	Chemical structure of MeSel

For research only, Do not use for Human!

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CAS No.	2901664-87-5
Purity	>98%
Formula	C21H17NSe
Mol Weight	362.33
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. da Rocha MJ, et al., 1-(Phenylselanyl)-2-(p-tolyl)indolizine: A selenoindolizine with potential antidepressant-like activity in mice mediated by the modulation of dopaminergic and noradrenergic systems. Brain Res. 2024 Jul 1;1834:148904.
CoA	CoA of MeSel

Smiles:	[Se](C=1C=CC=CC1)C=2C(=CN3C=CC=CC23)C=4C=CC(=CC4)C


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