MERS-CoV-IN-4

MERS-CoV-IN-4 is an orally active antiviral inhibitor targeting the MERS-CoV spike (S) protein, with an IC50 of 0.009 μM in Huh-7 cells, and Kd values of 7.72 μM for the full-length S protein and 5.09 μM for S-RBD. MERS-CoV-IN-4 inhibits viral entry, and suppresses MERS-CoV pseudoviruses and live viruses in vitro. MERS-CoV-IN-4 reduces pulmonary viral loads in hDPP4 transgenic mice. MERS-CoV-IN-4 can be used for research on Middle East respiratory syndrome coronavirus infection .


Cat. No.: EX-A17398	Purity: >98%

	Chemical structure of MERS-CoV-IN-4

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
5mg	456	Inquire
10mg	556	Inquire
25mg	656	Inquire

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CAS No.	2740494-38-4
Purity	>98%
Formula	C19H22N4S
Mol Weight	338.47

Reference:	[1].Dai K, et al. Discovery and evaluation of a 4-(benzothiazol-2-yl)-N-substituted aniline scaffold as MERS-CoV inhibitors. Eur J Med Chem. 2026 Oct 15;316:119055.
CoA	CoA of MERS-CoV-IN-4

Smiles:	C12=CC=CC=C1SC(C3=CC=C(NCCN4CCNCC4)C=C3)=N2


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